Parental perinatal depression and offspring psychotic experiences

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Parental depression and offspring psychopathology: a children of twins study.

BACKGROUND Associations between parental depression and offspring affective and disruptive disorders are well documented. Few genetically informed studies have explored the processes underlying intergenerational associations. METHOD A semi-structured interview assessing DSM-III-R psychiatric disorders was administered to twins (n=1296) from the Australian Twin Register (ATR), their spouses (n...

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Parental divorce, parental depression, and gender differences in adult offspring suicide attempt.

Research suggests parental divorce during childhood increases risk of suicide attempt for male but not female offspring. The negative impact on offspring associated with parental divorce may be better explained by parental psychopathology, such as depression. We examined whether adult offspring of parental divorce experience elevated risk of suicide attempt, controlling for parental history of ...

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Advanced paternal age and vulnerability to psychotic-like experiences in the offspring

OBJECTIVE To investigate whether advanced paternal age is associated with increased psychotic-like experiences (PLEs) and increased sensitivity to Cannabis in the offspring. METHODS A cross-sectional population-based study in 1684 participants aged 18 to 25. RESULTS We found no association of paternal age with PLEs. Only the positive dimension subscale was associated to paternal age, but th...

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Cannabis, COMT and psychotic experiences.

BACKGROUND A putative interaction between cannabis and variation at rs4680 within the catechol-methyl-transferase (COMT) gene on psychosis has been reported, but not adequately replicated. AIMS To examine whether the relative risk of developing psychosis following use of cannabis is dependent upon variation within COMT. METHOD A longitudinal study of 2630 individuals from the Avon Longitudi...

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Sun Exposure and Psychotic Experiences

OBJECTIVE Sun exposure is considered the single most important source of vitamin D. Vitamin D deficiency has been suggested to play a role in the etiology of psychotic disorders. The aim of the present study was to evaluate the association between sun exposure and psychotic experiences (PEs) in a general population sample of Swedish women. METHODS The study population included participants fr...

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ژورنال

عنوان ژورنال: The Lancet Psychiatry

سال: 2020

ISSN: 2215-0366

DOI: 10.1016/s2215-0366(20)30154-1